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QTOF breath samples from plasmodium falciparum CHMI trial
This data was collected as part of a study investigating the exhaled breath of volunteers undergoing controlled human malaria infection (CHMI) with Plasmoldium falciparum infection. Seven volunteers were recruited for the trial, and they provided breath samples both before and after drug treatment over a period of 28 days. The data also contains th... moree ambient air samples collected at the same time as the breath collection.
Two types of data are in this collection: GC-QTOF-MS file, with extension .D, which is proprietary to the company Agilent. The software "MassHunter", which is available to those who own any Agilent GC, LC or MS equipment, can be used to open these files. The second type of file available is of .xml type, which is an universal type and can be read using any text editor. less
Medicinal and Biomolecular Chemistry not elsewhere classified
17 Aug 2016
18 Nov 2016
controlled human malaria infection (CHMI)
volatile organic compounds (VOC)
The detailed description of collecting the data is in the paper.
Amalia Berna, James McCarthy, Michelle Michie, Florence Bravo, Julie Cassells
Creative Commons Attribution 4.0 International Licence
Berna, Amalia Z.; McCarthy, James S.; Michie, Michelle; Bravo, Florence; Cassells, Julie (2018): QTOF breath samples from plasmodium falciparum CHMI trial. v3. CSIRO. Data Collection.
All Rights (including copyright) CSIRO 2018.
The metadata and files (if any) are available to the public.
Novel sensor and biomarkers for diagnosis of malaria using human breath
The project aimed to validate the utility of the thioether compounds for diagnosis of diverse and naturally acquired malaria infections. We aimed to repeat a research clinic-based breath collection experiment in one of the ongoing Controlled Human Malaria Infection studies, with a much-increased density of breath collection.
CHMI breath collection
GC-QTOC analysis of human breath samples
Gas Chromatography Quadrupole-Time-of-Flight Mass Spectrometry (GC-QTOF-MS)
Amalia Z. Berna
James S. McCarthy