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QTOF breath samples from plasmodium falciparum CHMI trial

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About this Collection

QTOF breath samples from plasmodium falciparum CHMI trial


This data was collected as part of a study investigating the exhaled breath of volunteers undergoing controlled human malaria infection (CHMI) with Plasmoldium falciparum infection. Seven volunteers were recruited for the trial, and they provided breath samples both before and after drug treatment over a period of 28 days. The data also contains th... more


Medicinal and Biomolecular Chemistry not elsewhere classified


https://doi.org/10.25919/5b5b7530a39f4


17 Aug 2016


18 Nov 2016


Alisha Anderson
Alisha.Anderson@csiro.au

breath malaria P.falciparum biomarkers diagnosis controlled human malaria infection (CHMI) volatile organic compounds (VOC) mass spectrometry gas chromatography


:

Diurnal variation in expired breath volatiles in malaria-infected and healthy volunteers

Attribution

The detailed description of collecting the data is in the paper.


Amalia Berna, James McCarthy, Michelle Michie, Florence Bravo, Julie Cassells


Creative Commons Attribution 4.0 International Licence


CSIRO (Australia)


Berna, Amalia Z.; McCarthy, James S.; Michie, Michelle; Bravo, Florence; Cassells, Julie (2018): QTOF breath samples from plasmodium falciparum CHMI trial. v3. CSIRO. Data Collection. https://doi.org/10.25919/5b5b7530a39f4


All Rights (including copyright) CSIRO 2018.


The metadata and files (if any) are available to the public.

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About this Project

Novel sensor and biomarkers for diagnosis of malaria using human breath


The project aimed to validate the utility of the thioether compounds for diagnosis of diverse and naturally acquired malaria infections. We aimed to repeat a research clinic-based breath collection experiment in one of the ongoing Controlled Human Malaria Infection studies, with a much-increased density of breath collection.


Alisha Anderson


CHMI breath collection


GC-QTOC analysis of human breath samples


Experiment


Gas Chromatography Quadrupole-Time-of-Flight Mass Spectrometry (GC-QTOF-MS)


Amalia Z. Berna


James S. McCarthy


Michelle Michie


Florence Bravo


Julie Cassells


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